Structure and mechanism in protein science : a guide to enzyme catalysis and protein folding /

Fersht, Alan

Structure and mechanism in protein science : a guide to enzyme catalysis and protein folding / Alan Fersht. - xxi, 631 páginas : ilustraciones ; 24 cm.

Incluye contenido, índice

Referencias bibliográficas

1. The three-dimensional structure of proteins. -- 2. Chemical catalysis. -- 3. The basic equations of enzyme kinetics. -- 4. Measurement and magnitude of individual reate constants. -- 5. The pH Dependence of enzyme catalysis. -- 6. Practical methods for kinetics and equilibria. -- 7. Detection of intermediates in enzymatic reactions. -- 8. Stereochemistry of enzymatic reactions. -- 9. Active-site-directed and enzyme-activated irreversible inhibitors: "affiinity labels" and "suicide inhibitors". -- 10. Conformational change, allosteric regulation, motors, and work. -- 11. Forces between molecules, and binding energies. -- 12. Enzyme-substrate complementarity and the use of binding energy in catalysis. -- 13. Specificity and editing mechanisms. -- 14. Recombinant DNA technology. -- 15. Protein engineering. -- 19. Folding pathways and energy landscapes.

0716732688


Enzimas
Proteínas -- Estructura

572.7 / F399s 1999