TY  - BOOK
AU  - Fersht,Alan
TI  - Structure and mechanism in protein science : : a guide to enzyme catalysis and protein folding / 
SN  - 0716732688
U1  - 572.7  
PY  - 1999///
CY  - New York : 
PB  - W.H. Freeman , 
KW  - Enzimas
KW  - Proteínas
KW  -  Estructura
N1  - Incluye contenido, índice; Referencias bibliográficas; 1. The three-dimensional structure of proteins. -- 2. Chemical catalysis. -- 3. The basic equations of enzyme kinetics. -- 4. Measurement and magnitude of individual reate constants. -- 5. The pH Dependence of enzyme catalysis. -- 6. Practical methods for kinetics and equilibria. -- 7. Detection of intermediates in enzymatic reactions. -- 8. Stereochemistry of enzymatic reactions. -- 9. Active-site-directed and enzyme-activated irreversible inhibitors: "affiinity labels" and "suicide inhibitors". -- 10. Conformational change, allosteric regulation, motors, and work. -- 11. Forces between molecules, and binding energies. -- 12. Enzyme-substrate complementarity and the use of binding energy in catalysis. -- 13. Specificity and editing mechanisms. -- 14. Recombinant DNA technology. -- 15. Protein engineering. -- 19. Folding pathways and energy landscapes
UR  - http://www.bib.ufro.cl/applications/ppi/files/covers/a38973.jpg
UR  - http://www.bib.ufro.cl/applications/ppi/files/table-of-contents/a38973.pdf
ER  -