TY - GEN AU - Patrick, Graham L. TI - An introduction to medicinal chemistry SN - 9780198796589 U1 - 615.19 PY - 2018/// CY - Oxford : PB - Oxford University Press , KW - Química farmacéutica KW - Farmacología KW - Medicamentos KW - Química KW - Farmacia (Ciencia) KW - Medicina N1 - Incluye índice.; 1. Drugs and drug targets: an overview. -- 2. Protein structure and function. -- 3. Enzymes and enzyme inhibitors. -- 4. Receptors, agonists, and antagonists. -- 5. Receptors and signal transduction. -- 6. Nucleic acids as drug targets. -- 7. Miscellaneous drug targets. -- 8. Pharmacokinetics and related topics. -- 9. Drug discovery: finding a lead. -- 10. Drug design: optimizing target interactions. -- 11. Drug Design: optimizing access to the target. -- 12. Getting the drug to market. -- 13. Cholinergics, anticholinergics, and anticholinesterases. -- 14. Drugs acting on the adrenergic nervous system. -- 15. The opioid analgesics. -- 16. Anti-ulcer agents. -- 17. Antibacterial agents. -- 18. Antiviral agents. -- 19. Anticancer agents. -- 20. Combinatorial and parallel synthesis. -- 21. Computer in medicinal chemistry. -- 22. Quantitative structure-activity relationships (QSAR) ER -