000			02010cam a22003497a 4500
001			74052
005			20220330101000.0
007			ta
008			140402e1999 xxua gr 001 0 eng u
020			_a0716732688
035			_a(Sirsi) a38973
035			_a74052
040			_aufro _erda _bspa _cCL-TeU
041			_aInglés
082	0	4	_a572.7 _bF399s 1999
100	1		_aFersht, Alan
245	1	0	_aStructure and mechanism in protein science : _ba guide to enzyme catalysis and protein folding / _cAlan Fersht.
264			_aNew York : _bW.H. Freeman , _c1999.
300			_axxi, 631 páginas : _bilustraciones ; _c24 cm.
336			_2rdaconctent _atext _btxt
337			_2rdamedia _aunmediated _bn
338			_avolume _bnc _crdacarrier
349			_aLibro
500			_aIncluye contenido, índice
504			_aReferencias bibliográficas
505			_a1. The three-dimensional structure of proteins. -- 2. Chemical catalysis. -- 3. The basic equations of enzyme kinetics. -- 4. Measurement and magnitude of individual reate constants. -- 5. The pH Dependence of enzyme catalysis. -- 6. Practical methods for kinetics and equilibria. -- 7. Detection of intermediates in enzymatic reactions. -- 8. Stereochemistry of enzymatic reactions. -- 9. Active-site-directed and enzyme-activated irreversible inhibitors: "affiinity labels" and "suicide inhibitors". -- 10. Conformational change, allosteric regulation, motors, and work. -- 11. Forces between molecules, and binding energies. -- 12. Enzyme-substrate complementarity and the use of binding energy in catalysis. -- 13. Specificity and editing mechanisms. -- 14. Recombinant DNA technology. -- 15. Protein engineering. -- 19. Folding pathways and energy landscapes.
650	0	0	_aEnzimas
650	0	4	_aProteínas _x Estructura
856	4	0	_3Cubierta _uhttp://www.bib.ufro.cl/applications/ppi/files/covers/a38973.jpg
856	4	0	_3Contenido _uhttp://www.bib.ufro.cl/applications/ppi/files/table-of-contents/a38973.pdf
942			_cLIB _2ddc
999			_c74052 _d74052